Archives of Physical Medicine and Rehabilitation
Volume 89, Issue 12, Supplement , Pages S45-S50 , December 2008

Use of Diffusion Tensor Imaging to Examine Subacute White Matter Injury Progression in Moderate to Severe Traumatic Brain Injury

  • Gahl Greenberg, MD

      Affiliations

    • Department of Medical Imaging, Division of Neuroradiology, University Health Network, Toronto, ON, Canada
    • ,
  • David J. Mikulis, MD

      Affiliations

    • Research Institute, Division of Brain Imaging and Behaviour Systems, University Health Network, Toronto Western Division, Toronto, ON, Canada
    • Department of Medical Imaging, Division of Neuroradiology, University Health Network, Toronto, ON, Canada
    • ,
  • Kevin Ng, MBBS, FRANZCR

      Affiliations

    • Department of Medical Imaging, Division of Neuroradiology, University Health Network, Toronto, ON, Canada
    • ,
  • Danielle DeSouza, BSc

      Affiliations

    • Toronto Rehabilitation Institute, Toronto, ON, Canada
    • Graduate Department of Rehabilitation Sciences, University of Toronto, Toronto, ON, Canada
    • ,
  • Robin E. Green, PhD, CPsych

      Affiliations

    • Toronto Rehabilitation Institute, Toronto, ON, Canada
    • Graduate Department of Rehabilitation Sciences, University of Toronto, Toronto, ON, Canada
    • Corresponding Author InformationReprint requests to Robin Green, PhD, CPsych, Toronto Rehabilitation Institute, 550 University Ave, Toronto, ON, M5G 2A2, Canada

  • Image Result

    T2-weighted images with overlying grid from Functool software, showing the ROI selection. Abbreviations: ACC, anterior corpus callosum; DF, deep frontal white matter; DT, deep temporal white matter; P

    T2-weighted images with overlying grid from Functool software, showing the ROI selection. Abbreviations: ACC, anterior corpus callosum; DF, deep frontal white matter; DT, deep temporal white matter; PCC, posterior corpus callosum.

  • Image Result
    Box plot diagrams showing FA reduction in right and left frontal lobes (A, B) and right and left temporal lobes (C, D), respectively. Mean, first to third quartiles and minimum and maximum scores are

    Box plot diagrams showing FA reduction in right and left frontal lobes (A, B) and right and left temporal lobes (C, D), respectively. Mean, first to third quartiles and minimum and maximum scores are indicated. For each pair of box plots, the left box plot contains values from the 4.5 month postinjury scan; the right box plot contains 2.5 year postinjury scan values. FA values, presented on the Y axis, range from .2 to .5 (A, B); .15 to .4 (C), and .15 to .45 (D).

 Supported by the Canadian Institutes of Health Research, the Physicians' Services Incorporated, and the Ontario Mental Health Foundation (grant nos. MOP-67072, 05-50, 2005-ABI-392).

 No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit on the authors or on any organization with which the authors are associated.

PII: S0003-9993(08)01407-X

doi: 10.1016/j.apmr.2008.08.211

Archives of Physical Medicine and Rehabilitation
Volume 89, Issue 12, Supplement , Pages S45-S50 , December 2008

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