Archives of Physical Medicine and Rehabilitation
Volume 89, Issue 12, Supplement , Pages S35-S44 , December 2008

Magnetic Resonance Imaging Evidence of Progression of Subacute Brain Atrophy in Moderate to Severe Traumatic Brain Injury

  • Kevin Ng, MBBS, FRANZCR

      Affiliations

    • Department of Medical Imaging, Division of Neuroradiology, University Health Network, University of Toronto, Toronto, ON, Canada
    • ,
  • David J. Mikulis, MD

      Affiliations

    • Department of Medical Imaging, Division of Neuroradiology, University Health Network, University of Toronto, Toronto, ON, Canada
    • ,
  • Joanna Glazer, MSc

      Affiliations

    • Graduate Department of Rehabilitation Sciences, University of Toronto, Toronto, ON, Canada
    • ,
  • Noor Kabani, PhD

      Affiliations

    • Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    • ,
  • Christine Till, PhD

      Affiliations

    • Toronto Rehabilitation Institute, Toronto, ON, Canada
    • ,
  • Gahl Greenberg, MD

      Affiliations

    • Department of Medical Imaging, Division of Neuroradiology, University Health Network, University of Toronto, Toronto, ON, Canada
    • ,
  • Andrew Thompson, MBBS, FRANZCR

      Affiliations

    • Department of Medical Imaging, Division of Neuroradiology, University Health Network, University of Toronto, Toronto, ON, Canada
    • ,
  • Dorothy Lazinski, MD

      Affiliations

    • Department of Medical Imaging, Division of Neuroradiology, University Health Network, University of Toronto, Toronto, ON, Canada
    • ,
  • Ronit Agid, MD

      Affiliations

    • Department of Medical Imaging, Division of Neuroradiology, University Health Network, University of Toronto, Toronto, ON, Canada
    • ,
  • Brenda Colella, MA

      Affiliations

    • Toronto Rehabilitation Institute, Toronto, ON, Canada
    • ,
  • Robin E. Green, PhD, CPsych

      Affiliations

    • Graduate Department of Rehabilitation Sciences, University of Toronto, Toronto, ON, Canada
    • Toronto Rehabilitation Institute, Toronto, ON, Canada
    • Corresponding Author InformationReprint requests to Robin Green, PhD, CPsych, 550 University Ave, Room 11004, Toronto, ON, Canada, M5G 2A2

  • Image Result

    Example of lesion progression from 4.5 months postinjury (left) to 2.5 years postinjury (right) in 2 different patients. Top, T2 axial images demonstrate significant progression of localized atrophy o

    Example of lesion progression from 4.5 months postinjury (left) to 2.5 years postinjury (right) in 2 different patients. Top, T2 axial images demonstrate significant progression of localized atrophy of the right temporal pole extending posteriorly to the mid right temporal lobe that lies superior to the petrous temporal bone. There is also localized dilatation of the right temporal horn. Bottom, FLAIR axial images demonstrate marked progression of localized atrophy in the right frontal lobe with associated adjacent gliosis, where there were only subtle changes on the initial MRI.

 Supported by the Canadian Institutes of Health Research and the Physicians' Services Inc (grant nos. MOP-67072, 05-50) and the Toronto Rehabilitation Institute, which receives funding under the Provincial Rehabilitation Research Program from the Ministry of Health and Long-Term Care in Ontario.

 No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit on the authors or on any organization with which the authors are associated.

PII: S0003-9993(08)01406-8

doi: 10.1016/j.apmr.2008.07.006

Archives of Physical Medicine and Rehabilitation
Volume 89, Issue 12, Supplement , Pages S35-S44 , December 2008

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