Archives of Physical Medicine and Rehabilitation
Volume 89, Issue 10 , Pages 1907-1912 , October 2008

Poststroke Upper-Limb Rehabilitation Using 5 to 7 Inserted Microstimulators: Implant Procedure, Safety, and Efficacy for Restoration of Function

  • Ross Davis, MD

      Affiliations

    • Alfred Mann Foundation, Santa Clarita, CA
    • Corresponding Author InformationReprint requests to Ross Davis, MD, Alfred Mann Foundation, 25134 Rye Canyon Loop, Santa Clarita, CA 91355
    • ,
  • Owen Sparrow, FRCS

      Affiliations

    • Southampton University Hospitals NHS Trust, Southampton, UK
    • ,
  • Gregoire Cosendai, PhD

      Affiliations

    • Alfred Mann Foundation, Santa Clarita, CA
    • ,
  • Jane H. Burridge, PhD

      Affiliations

    • University of Southampton, Southampton, UK
    • ,
  • Christian Wulff, MD

      Affiliations

    • Southampton University Hospitals NHS Trust, Southampton, UK
    • ,
  • Ruth Turk, MSc

      Affiliations

    • University of Southampton, Southampton, UK
    • ,
  • Joseph Schulman, PhD

      Affiliations

    • Alfred Mann Foundation, Santa Clarita, CA

References 

  1. Mann GE, Burridge JH, Malone LJ, Strike PW. A pilot study to investigate the effects of electrical stimulation on hand function and sensation in stroke. Neuromodulation. 2005;8:193–202
  2. Popovic DB, Popovic MB, Sinkjaer T, Stefanovic A, Schwirtlich L. Therapy of paretic arm in hemiplegic subjects augmented with a neural prosthesis: a cross-over study. Can J Physiol Pharmacol. 2004;82:749–756
  3. Chae J. Neuromuscular electrical stimulation for motor relearning in hemiparesis. Phys Med Rehabil Clin N Am. 2003;14:93–109
  4. De Kroon JR, IJzerman MJ, Chae J, Lankhorst GJ, Zilvold G. Relation between stimulation characteristics and clinical outcome in studies using electrical stimulation to improve motor control of the upper extremity in stroke. J Rehabil Med. 2005;37:65–74
  5. Alon G, McBride K, Ring H. Improving selected hand functions using a noninvasive neuroprosthesis in persons with chronic stroke. J Stroke Cerebrovasc Dis. 2002;11:99–106
  6. Chae J, Hart R. Intramuscular hand neuroprosthesis for chronic stroke survivors. Neurorehabil Neural Repair. 2003;17:109–117
  7. Turk R, Burridge JH, Davis R, et al. Therapeutic effectiveness of electric stimulation of the upper-limb poststroke using implanted microstimulators. Arch Phys Med Rehabil. 2008;89:1913–1922
  8. Brull R, Perlas A, Chan V. Ultrasound-guided peripheral nerve blockade. Curr Pain Headache Rep. 2007;11:25–32

 Supported by the Alfred Mann Foundation.

 A commercial party having a direct financial interest in the results of the research supporting this article may confer a financial benefit on the author or one or more of the authors. The Alfred Mann Foundation is developing the radiofrequency microstimulator used in this study. Davis and Cosendai are consultants to the Alfred Mann Foundation; Schulman was an employee of the Alfred Mann Foundation while the study was conducted.

 Published online August 29, 2008 at www.archives-pmr.org.

PII: S0003-9993(08)00432-2

doi: 10.1016/j.apmr.2008.05.010

Archives of Physical Medicine and Rehabilitation
Volume 89, Issue 10 , Pages 1907-1912 , October 2008

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