Archives of Physical Medicine and Rehabilitation
Volume 89, Issue 7 , Pages 1221-1229 , July 2008

The Effect of Exercise Training in Improving Motor Performance and Corticomotor Excitability in People With Early Parkinson's Disease

Presented in part to the Society for Neuroscience, October 17, 2006, Atlanta, GA; American Physical Therapy Association Combined Sections, February 1–5, 2006, San Diego, CA; the World Parkinson Congress, February 22–26, 2006, Washington, DC; and the National Parkinson Foundation Collaboration for Care Leadership Conference, October 20–22, 2005, San Francisco, CA.

  • Beth E. Fisher, PhD

      Affiliations

    • Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA
    • Division of Neurology, University of Southern California, Los Angeles, CA
    • Corresponding Author InformationCorrespondence to Beth Fisher, PhD, Div of Biokinesiology and Physical Therapy, University of Southern California, 1540 E Alcazar St, CHP 155, Los Angeles, CA 90089-9006
    • ,
  • Allan D. Wu, MD

      Affiliations

    • Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA.
    • ,
  • George J. Salem, PhD

      Affiliations

    • Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA
    • ,
  • Jooeun Song, MS

      Affiliations

    • Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA
    • ,
  • Chien-Ho (Janice) Lin, PhD

      Affiliations

    • Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA
    • ,
  • Jeanine Yip, DPT

      Affiliations

    • Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA
    • ,
  • Steven Cen, PhD

      Affiliations

    • Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA
    • ,
  • James Gordon, EdD

      Affiliations

    • Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA
    • ,
  • Michael Jakowec, PhD

      Affiliations

    • Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA
    • Division of Neurology, University of Southern California, Los Angeles, CA
    • ,
  • Giselle Petzinger, MD

      Affiliations

    • Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA
    • Division of Neurology, University of Southern California, Los Angeles, CA

  • Image Result

    The percentage change (post- pre-exercise/preexercise × 100) in motor performance measures are shown for each of the 3 exercise groups: zero, low, and high intensity. (A) Percentage change in stride l

    The percentage change (post- pre-exercise/preexercise × 100) in motor performance measures are shown for each of the 3 exercise groups: zero, low, and high intensity. (A) Percentage change in stride length (in meters) for each group. Stride length is the distance from right-heel contact to the following right-heel contact. (B) Percentage change in hip angle ROM (in degrees) or hip joint excursion for each group. (C) Percentage change in ankle angle ROM (in degrees) or ankle joint excursion for each group.

  • Image Result
    Pre- and postexercise measures of maximal CSP duration (in milliseconds) for subjects in the (A) zero-intensity, (B) low-intensity, and (C) high-intensity groups. Four subjects within the zero-intensi

    Pre- and postexercise measures of maximal CSP duration (in milliseconds) for subjects in the (A) zero-intensity, (B) low-intensity, and (C) high-intensity groups. Four subjects within the zero-intensity group participated in the TMS studies compared with 6 subjects in the low-intensity and 5 subjects in the high-intensity exercise groups. The thick black lines represent the average pre-CSP and post-CSP for each group.

 Supported by the Kinetics Foundation and National Institute of Neurological Disorders and Stroke (grant no. K23-NS045764).

 No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit on the author(s) or on any organization with which the author(s) is/are associated.

 Reprints are not available from the author.

 Published online June 5, 2008 at www.archives-pmr.org.

PII: S0003-9993(08)00235-9

doi: 10.1016/j.apmr.2008.01.013

Archives of Physical Medicine and Rehabilitation
Volume 89, Issue 7 , Pages 1221-1229 , July 2008

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