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Volume 89, Issue 1 , Pages 16-23 , January 2008

Biochemicals Associated With Pain and Inflammation are Elevated in Sites Near to and Remote From Active Myofascial Trigger Points

Jay P. Shah, MD
- Rehabilitation Medicine Department, National Institutes of Health, Clinical Center, Bethesda, MD
- Correspondence to Jay P. Shah, MD, Rehabilitation Medicine Dept, Clinical Research Center, National Institutes of Health, 10 Center Dr, Rm 1-1469, MSC 1604, Bethesda, MD, 20892
Jerome V. Danoff, PhD, PT
- Rehabilitation Medicine Department, National Institutes of Health, Clinical Center, Bethesda, MD
- Department of Exercise Science, George Washington University, Washington, DC
Mehul J. Desai, MD
- Department of Anesthesiology and Critical Care Medicine, George Washington University, Washington, DC
Sagar Parikh, BA
- Rehabilitation Medicine Department, National Institutes of Health, Clinical Center, Bethesda, MD
Lynn Y. Nakamura, MD
- National Rehabilitation Hospital, Washington, DC
Terry M. Phillips, PhD, DSc
- National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering, Ultramicro Analytical Immunochemistry Resource, Bethesda, MD
Lynn H. Gerber, MD
- College of Health and Human Services, Center for the Study of Chronic Illness and Disability, George Mason University, Fairfax, VA.

Microdialysis needle.

Microdialysis needle.
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Analyte concentrations in the trapezius combining previous and current data. Collection for (A) pH and (B) SP.

Analyte concentrations in the trapezius combining previous and current data. Collection for (A) pH and (B) SP.
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Analyte concentrations in the trapezius for (A) CGRP and (B) bradykinin.

Analyte concentrations in the trapezius for (A) CGRP and (B) bradykinin.
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Analyte concentrations in the trapezius for (A) TNF-α and (B) IL-1β.

Analyte concentrations in the trapezius for (A) TNF-α and (B) IL-1β.
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Analyte concentrations in the trapezius for (A) IL-6 and (B) IL-8.

Analyte concentrations in the trapezius for (A) IL-6 and (B) IL-8.
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Analyte concentrations in the trapezius for (A) 5-HT and (B) norepinephrine.

Analyte concentrations in the trapezius for (A) 5-HT and (B) norepinephrine.
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Analyte concentrations in the trapezius compared with the gastrocnemius for (A) pH and (B) bradykinin.

Analyte concentrations in the trapezius compared with the gastrocnemius for (A) pH and (B) bradykinin.
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Analyte concentrations in the trapezius compared with the gastrocnemius for (A) SP and (B) norepinephrine.

Analyte concentrations in the trapezius compared with the gastrocnemius for (A) SP and (B) norepinephrine.
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Analyte concentrations in the trapezius compared with the gastrocnemius for (A) TNF-α and (B) IL-6.

Analyte concentrations in the trapezius compared with the gastrocnemius for (A) TNF-α and (B) IL-6.
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Supported by the Intramural Research Program, National Institutes of Health (NIH), the Clinical Center and Office of the Director, NIH.A commercial party having a direct financial interest in the results of the research supporting this article has conferred or will confer a financial benefit upon the author or 1 or more of the authors. Shah, Danoff, Phillips, and Gerber have filed a patent application for the device used in this study.

PII: S0003-9993(07)01752-2

doi: 10.1016/j.apmr.2007.10.018

« Previous Next » Archives of Physical Medicine and Rehabilitation
Volume 89, Issue 1 , Pages 16-23 , January 2008