Archives of Physical Medicine and Rehabilitation
Volume 89, Issue 1 , Pages 56-61 , January 2008

Effect of Botulinum Toxin Injection in the Rectus Femoris on Stiff-Knee Gait in People With Stroke: A Prospective Observational Study

  • Gaëtan G. Stoquart, MD

      Affiliations

    • Rehabilitation and Physical Medicine Unit, Université Catholique de Louvain, Brussels, Belgium
    • Department of Physical Medicine and Rehabilitation, Université Catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, Belgium
  • ,
  • Christine Detrembleur, PhD

      Affiliations

    • Rehabilitation and Physical Medicine Unit, Université Catholique de Louvain, Brussels, Belgium
  • ,
  • Sara Palumbo, MD

      Affiliations

    • Department of Physical Medicine and Rehabilitation, Université Catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, Belgium
  • ,
  • Thierry Deltombe, MD

      Affiliations

    • Department of Physical Medicine and Rehabilitation, Université Catholique de Louvain, Cliniques Universitaires de Mont-Godinne, Yvoir, Belgium.
  • ,
  • Thierry M. Lejeune, MD, PhD

      Affiliations

    • Rehabilitation and Physical Medicine Unit, Université Catholique de Louvain, Brussels, Belgium
    • Department of Physical Medicine and Rehabilitation, Université Catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, Belgium
    • Corresponding Author InformationReprint requests to Thierry M. Lejeune, MD, PhD, Dept of Physical Medicine and Rehabilitation, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Ave Hippocrate 10, B-1200 Brussels, Belgium

  • Image Result

    The typical trace of 1 patient walking at .55m/s. (A) The knee angular displacement (d), (B) knee angular speed (s), (C) net knee joint moment (m), (D) knee joint power (p), and (E) vastus medialis (V

    The typical trace of 1 patient walking at .55m/s. (A) The knee angular displacement (d), (B) knee angular speed (s), (C) net knee joint moment (m), (D) knee joint power (p), and (E) vastus medialis (VM), vastus lateralis (VL), biceps femoris (BF), and rectus femoris (RF) activation time are presented as a function of gait cycle time (in percent). Grey areas represent values (mean ± SD) of healthy subjects walking at .55m/s. Dashed grey lines and solid black lines represent, respectively, pre– and post–BTX-A data of the patient. The vertical dashed line symbolizes the transition between the stance and swing phases. Arrows show key data selected for each variable in all patients on every assessment. Abbreviation: SL, slope of the linear regression fitted to the knee angular speed between s1 and s3.

 Supported by the Association Nationale d’Aide aux personnes Handicapées (ANAH-Rotary Belgium and Luxemburg), the Fondation du Patrimoine (Université Catholique de Louvain, Brussels), the Fonds National de la Recherche Scientifique, and the Fonds Spécial de Recherche. Botulinum toxin type A (Botox) was provided by Allergan.No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.

PII: S0003-9993(07)01614-0

doi: 10.1016/j.apmr.2007.08.131

Archives of Physical Medicine and Rehabilitation
Volume 89, Issue 1 , Pages 56-61 , January 2008