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Volume 88, Issue 10, Pages 1289-1297 (October 2007)


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Development of a French Isometric Strength Normative Database for Adults Using Quantitative Muscle Testing

Jean-Yves Hogrel, PhDaCorresponding Author Informationemail address, Christine A. Payan, MDa, Gwenn Ollivier, PTa, Véronique Tanant, PTd, Shahram Attarian, MDe, Annabelle Couillandre, PhD, PTa, Arnaud Dupeyron, MDf, Lucette Lacomblez, MD, PhDb, Valérie Doppler, MDa, Vincent Meininger, MDc, Christine Tranchant, MD, PhDf, Jean Pouget, MDe, Claude Desnuelle, MD, PhDd

Abstract 

Hogrel J-Y, Payan CA, Ollivier G, Tanant V, Attarian S, Couillandre A, Dupeyron A, Lacomblez L, Doppler V, Meininger V, Tranchant C, Pouget J, Desnuelle C. Development of a French isometric strength normative database for adults using quantitative muscle testing.

Objective

To establish a normative database for isometric strength measured by quantitative muscle testing (QMT) for a French adult population.

Design

Measurement of maximal voluntary isometric contraction.

Setting

Four clinical centers involved in neuromuscular disorders.

Participants

A total of 315 healthy adults (147 men, 168 women) ages 20 to 80 years.

Interventions

Not applicable.

Main Outcome Measure

Isometric torque values of 14 muscle functions (13 bilaterally and neck).

Results

This study led to the development of a French isometric strength normative database for adults measured by QMT. For each muscle function, predictive regression models using age, sex, and weight are proposed. Some methodologic issues concerning strength measurement are discussed.

Conclusions

This database can be used to compute relative deficits in muscle strength for 27 muscle functions and also to estimate composite scores for follow-up of patients either during the natural history of their disease or during a therapeutic trial.

a Institut de Myologie, GH Pitié-Salpêtrière, Paris, France

b Département de Pharmacologie Clinique, GH Pitié-Salpêtrière, Paris, France

c Fédération des Maladies du Système Nerveux, GH Pitié-Salpêtrière, Paris, France

d Centre de Référence Maladies Neuromusculaires, Hôpital de l’Archet, Nice, France

e Service de Neurologie, CHU La Timone, Marseille, France

f Service de Neurologie, CHU de Strasbourg, Strasbourg, France.

Corresponding Author InformationReprint requests to Jean-Yves Hogrel, PhD, Institut de Myologie, GH Pitié-Salpêtrière, 75651 Paris Cedex 13, France

 Supported by the Association de Recherche sur la Sclérose Latérale Amyotrophique and the Association Française contre les Myopathies.

 No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.

PII: S0003-9993(07)01282-8

doi:10.1016/j.apmr.2007.07.011


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