Presented in part to the American Academy of Physical Medicine and Rehabilitation on October 10, 2004, Phoenix, AZ.
Abstract
Haziza M, Kremer R, Benedetti A, Trojan DA. Osteoporosis in a postpolio clinic population.
Objectives
To determine (1) the frequency of osteoporosis at the hip and lumbar spine in a postpolio clinic population and (2) the association of lower-extremity muscle strength and other potential contributing factors to osteoporosis with bone density measured at the hip.
Design
Cross-sectional study involving a chart review.
Setting
A university-affiliated hospital postpolio clinic.
Participants
Patient charts (N=379) were reviewed; 164 (26%) were included, and 215 (74%) were not included primarily (74%) because of the unavailability of bone density results.
Interventions
Not applicable.
Main Outcome Measures
Bone density (in g/cm2) and T score were assessed at the femoral neck and lumbar spine. Muscle strength was evaluated by manual muscle testing in 7 bilateral lower-extremity muscles.
Results
The occurrence of osteoporosis at the hip and lumbar spine was 20 (32%) of 62 and 6 (10%) of 61 in men, 3 (9%) of 33 and 2 (6%) of 32 in premenopausal women, and 18 (27%) of 67 and 7 (11%) of 65 in postmenopausal women, respectively. In a logistic regression model, the presence of osteoporosis at the hip was significantly associated with strength sum score in the same extremity in which the bone density was performed after adjusting for other important risk factors (age, body mass index, time since polio).
Conclusions
Osteoporosis occurred commonly at the hip in a postpolio clinic population. Hip bone density was associated with muscle strength in the same lower extremity.
aDepartment of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University Health Centre, McGill University, Montreal, QC, Canada
bEndocrinology Division, Department of Medicine, McGill University Health Centre, McGill University, Montreal, QC, Canada
cDepartments of Medicine and Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada
dDepartment of Medicine, l’Université de Montréal, Montreal, QC, Canada.
Correspondence to Daria A. Trojan, MD, Montreal Neurological Hospital, McGill University Health Centre, 3801 University St, Montreal, QC H3A 2B4, Canada
Supported by the Polio Quebec Association and the Montreal Neurological Institute (salary support).
No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.