Archives of Physical Medicine and Rehabilitation
Volume 88, Issue 3, Supplement 1 , Pages S76-S83 , March 2007

Spinal Cord Injury Medicine. 5. Long-Term Medical Issues and Health Maintenance

  • Anthony E. Chiodo, MD

      Affiliations

    • Department of Physical Medicine and Rehabilitation, University of Michigan Hospital, Ann Arbor, MI
    • Corresponding Author InformationCorrespondence to Anthony E. Chiodo, MD, Dept of PM&R, Univ of Michigan Hospital, 325 E Eisenhower, Ann Arbor, MI
    • ,
  • William M. Scelza, MD

      Affiliations

    • Department of Physical Medicine and Rehabilitation, Carolinas Rehabilitation, Charlotte, NC
    • ,
  • Steven C. Kirshblum, MD

      Affiliations

    • Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry–New Jersey Medical School, Newark, NJ
    • Spinal Cord Injury Services, Kessler Institute for Rehabilitation, West Orange, NJ
    • ,
  • Lisa-Ann Wuermser, MD

      Affiliations

    • Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN
    • ,
  • Chester H. Ho, MD

      Affiliations

    • and Louis Stokes Cleveland Department of Veterans Affairs Medical Center and Department of Physical Medicine and Rehabilitation, Case Western Reserve University, Cleveland, OH.
    • ,
  • Michael M. Priebe, MD

      Affiliations

    • Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN

References 

  1. Key reference.

  2. McKinley WO, Jackson AB, Cardenas DD, DeVivo MJ. Long-term medical complications after traumatic spinal cord injury: a regional Model Systems analysis. Arch Phys Med Rehabil. 1999;80:1402–1410

    ⁎

  3. Cardenas DD, Hoffman JM, Kirshblum S, McKinley W. Etiology and incidence of rehospitalization after traumatic spinal cord injury: a multicenter analysis. Arch Phys Med Rehabil. 2004;85:1757–1763

    ⁎

  4. Krause JS, Broderick L. Patterns of recurrent pressure ulcers after spinal cord injury: identification of risk and protective factors 5 or more years after onset. Arch Phys Med Rehabil. 2004;85:1257–1264
  5. Consortium for Spinal Cord Medicine Clinical Practice Guidelines. Pressure ulcer prevention and treatment following spinal cord injury: a clinical practice guideline for health-care professionals. J Spinal Cord Med. 2001;24(Suppl 1):S40–S101

    ⁎

  6. Consortium Guidelines for Spinal Cord Medicine Clinical Practice Guidelines. Urological management. Washington (DC): Paralyzed Veterans of America; 2006;

    ⁎

  7. Morton SC, Shekelle PG, Adams JL, et al. Antimicrobial prophylaxis for urinary tract infection in persons with spinal cord dysfunction. Arch Phys Med Rehabil. 2002;83:129–138
  8. Hajebrahimi S, Altaweel W, Cadoret J, Cohen E, Corcos J. Efficacy of botulinum-A toxin in adults with neurogenic overactive bladder: initial results. Can J Urol. 2005;12:2543–2546
  9. Watanabe T, Yokoyama T, Sasaki K, Nozaki K, Ozawa H, Kumon H. Intravesical resiniferatoxin for patients with neurogenic detrusor overactivity. Int J Urol. 2004;11:200–205
  10. Ost MC, Lee BR. Urolithiasis in patients with spinal cord injuries: risk factors, management, and outcomes. Cur Opin Urol. 2006;16:93–99
  11. Hess MJ, Zhan EH, Foo DK, Yalla SV. Bladder cancer in patients with spinal cord injury. J Spinal Cord Med. 2003;26:335–338
  12. Consortium for Spinal Cord Medicine. Respiratory management following spinal cord injury: a clinical practice guideline for health-care professionals. J Spinal Cord Med. 2005;28:259–293
  13. Berlowitz DJ, Brown DJ, Campbell DA, Pierce RJ. A longitudinal evaluation of sleep and breathing in the first year after cervical spinal cord injury. Arch Phys Med Rehabil. 2005;86:1193–1199
  14. Burns SP, Rad MY, Bryant S, Kapur V. Long-term treatment of sleep apnea in persons with spinal cord injury. Am J Phys Med Rehabil. 2005;84:620–626
  15. Lazo MG, Shirazi P, Sam M, Giobbie-Hurder A, Blacconiere MJ, Muppidi M. Osteoporosis and risk of fracture in men with spinal cord injury. Spinal Cord. 2001;39:208–214
  16. Moran de Brito CM, Battistella LR, Saito ET, Sakamoto H. Effect of alendronate on bone mineral density in spinal cord injury patients: a pilot study. Spinal Cord. 2005;43:341–348
  17. Eser P, de Bruin ED, Telley I, Lechner HE, Knecht H, Stussi E. Effect of electrical stimulation-induced cycling on bone mineral density in spinal cord-injured patients. Eur J Clin Invest. 2003;33:412–419
  18. Milone SD, Milone SL. Evidence-based periodic health examination of adults (Memory aid for primary care physicians). Can Fam Physician. 2006;52:40–47
  19. Collins EG, Langbein WE, Smith B, Hendricks R, Hammond M, Weaver F. Patients’ perspective on the comprehensive preventive health evaluation in veterans with spinal cord injury. Spinal Cord. 2005;43:366–374
  20. Choi H, Binder DS, Oropilla ML, et al. Evaluation of selected laboratory components of a comprehensive periodic health evaluation for veterans with spinal cord injury and disorders. Arch Phys Med Rehabil. 2006;87:603–610
  21. Boland BJ, Wollan PC, Silverstein MD. Review of systems, physical examination, and routine tests for case-finding in ambulatory patients. Am J Med Sci. 1995;309:194–200
  22. Razden S, Leboeuf L, Meinbach DS, Weinstein D, Gousse AE. Current practice patterns in the urologic surveillance and management of patients with spinal cord injury. Urology. 2003;61:893–896
  23. Ozer MN, Shannon SR. Renal sonography in asymptomatic persons with spinal cord injury: a cost-effectiveness analysis. Arch Phys Med Rehabil. 1991;72:35–37
  24. Sipski ML, Estores IM, Alexander CJ, Guo X, Chandralapaty SK. Lack of justification for routine abdominal ultrasonography in patients with chronic spinal cord injury. J Rehabil Res Dev. 2004;41:101–108
  25. Tins B, Teo HG, Popuri R, Cassar-Pullicino V, Tyrrell P. Follow-up imaging of the urinary tract in spinal injury patients: is a KUB necessary with every ultrasound?. Spinal Cord. 2005;43:219–222
  26. Sepahpanah F, Burns SP, McKnight B, Yang CC. Role of creatinine clearance as a screening test in persons with spinal cord injury. Arch Phys Med Rehabil. 2006;87:524–528
  27. Weaver FM, Goldstein B, Evans CT, et al. Influenza vaccination among veterans with spinal cord injury: part 2. Increasing vaccination rates. J Spinal Cord Med. 2003;26:210–218
  28. Donnelly C, McColl MA, Charlifue S, et al. Utilization, access and satisfaction with primary care among people with spinal cord injuries: a comparison of three countries. Spinal Cord. 2007;45:25–36
  29. Jackson A, Wadley V. A multicenter study of women’s self-reported reproductive health after spinal cord injury. Arch Phys Med Rehabil. 1999;80:1420–1428
  30. Nosek MA, Wuermser L, Walter LJ. Difference in contraceptive methods used by women with physical disabilities compared to women without disabilities. Prim Care Update Ob Gyns. 1998;5:172–173
  31. ACOG Committee Opinion. Number 275, September 2002 (Obstetric management of patients with spinal cord injuries). Obstet Gynecol. 2002;100:625–627
  32. Matzarogluo C, Assimakopoulos K, Panagiotopoulos E, Kasimatis G, Dimakopoulos P, Lambiris E. Sexual function in females with severe cervical spinal cord injuries: a controlled study with the Female Sexual Function Index. Int J Rehabil Res. 2005;28:375–377
  33. Sipski ML, Alexander CJ, Rosen R. Sexual arousal and orgasm in women: effects of spinal cord injury. Ann Neurol. 2001;49:35–44
  34. Sipski ML, Rosen RC, Alexander CJ, Hamer RM. Sildenafil effects on sexual and cardiovascular responses in women with spinal cord injury. Urology. 2000;55:812–815
  35. Komisaruk BR, Whipple B, Crawford A, Liu WC, Kalnin A, Mosier K. Brain activation during vaginocervical self stimulation and orgasm in women with complete spinal cord injury: fMRI evidence of mediation by the vagus nerves. Brain Res. 2004;1024:77–88
  36. Smeltzer SC. Preventive health screening for breast and cervical cancer and osteoporosis in women with physical disabilities. Fam Community Health. 2005;29(1 Suppl):35S–43S
  37. Broderick LE, Krause JS. Breast and gynecologic health-screening behaviors among 191 women with spinal cord injuries. J Spinal Cord Med. 2003;26:145–149
  38. Slade JM, Bickel CS, Modlesky CM, Majumdar S, Dudley GA. Trabecular bone is more deteriorated in spinal cord injured versus estrogen-free postmenopausal women. Osteoporos Int. 2005;16:263–272
  39. Bors E, Comarr EE. Neurological disturbances of sexual function with special reference to 529 patients with spinal cord injury. Urol Survey. 1960;110:191–221
  40. Derry F, Hultling C, Seftel AD, Sipski ML. Efficacy and safety of oral sildenafil citrate (Viagra) in men with erectile dysfunction and spinal cord injury: a review. Urology. 2002;60(2 Suppl 2):49–57
  41. Linsenmeyer TA. Sexual function and infertility following spinal cord injury. Phys Med Rehabil Clin N Am. 2000;11:141–156
  42. Sonksen J, Biering-Sorensen F, Kristensen JK. Ejaculation induced by penile vibratory stimulation in men with spinal cord lesion. Paraplegia. 1994;32:651–660
  43. Hultling C, Rosenlund B, Levi R, Fridstrom M, Sjoblom P, Hillensjo T. Assisted ejaculation and in-vitro fertilization in the treatment of infertile spinal cord-injured men: the role of intracytoplasmic sperm injection. Hum Reprod. 1997;12:499–502
  44. Barrett H, McClelland JM, Rutkowski SB, Siddall PJ. Pain characteristics in patients admitted to hospital with complications after spinal cord injury. Arch Phys Med Rehabil. 2003;84:789–795
  45. Warms CA, Turner JA, Marshall HM, Cardenas DD. Treatments for chronic pain associated with spinal cord injuries: many are tried, few are helpful. Clin J Pain. 2002;18:154–163
  46. Ravenscroft A, Ahmed YS, Burnside IG. Chronic pain after SCI: a patient survey. Spinal Cord. 2000;38:611–614
  47. Bryce TN, Ragnarsson KT. Pain after spinal cord injury. Phys Med Rehabil Clin N Am. 2000;11:157–168

    ⁎

  48. Werhagen L, Budh CN, Hultling C, Molander C. Neuropathic pain after traumatic spinal cord injury—relations to gender, spinal level, completeness, and age at the time of injury. Spinal Cord. 2004;42:665–673
  49. Siddall PJ, Taylor DA, McClelland JM, Rutkowski SB, Cousins MJ. Pain report and the relationship of pain to physical factors in the first 6 months following spinal cord injury. Pain. 1999;81:187–197
  50. Dalyan M, Cardenas DD, Gerard B. Upper extremity pain after spinal cord injury. Spinal Cord. 1999;37:191–195
  51. Salisbury SK, Choy NL, Nitz J. Shoulder pain, range of motion, and functional motor skills after acute tetraplegia. Arch Phys Med Rehabil. 2003;84:1480–1485
  52. Dyson-Hudson TA, Kirshblum SC. Shoulder pain in chronic spinal cord injury, part I: epidemiology, etiology, and pathomechanics. J Spinal Cord Med. 2004;27:4–17

    ⁎

  53. Norrbrink Budh C, Lundeberg T. Use of analgesic drugs in individuals with spinal cord injury. J Rehabil Med. 2005;37:87–94
  54. Curtis KA, Tyner TM, Zachary L, et al. Effect of a standard exercise protocol on shoulder pain in long-term wheelchair users. Spinal Cord. 1999;37:421–429
  55. Ramer LM, Ramer MS, Steeves JD. Setting the stage for functional repair of spinal cord injuries: a cast of thousands. Spinal Cord. 2005;43:134–161
  56. Wuermser LA, Ho CH, Chiodo AE, Priebe MM, Kirshblum SC, Scelza WM. Spinal cord injury medicine (2. Acute care management of traumatic and nontraumatic injury). Arch Phys Med Rehabil. 2007;88(3 Suppl 1):S55–S61
  57. Bracken MB, Holford TR. Effect of timing of methylprednisolone or naloxone administration on recovery of segmental and long-tract neurological function in NASCIS 2. J Neurosurg. 1993;79:500–507
  58. Geisler FH, Dorsey FC, Coleman WP. Recovery of motor function after spinal cord injury: a randomized, placebo controlled trial with GM-1 ganglioside [published erratum in: N Engl J Med 1991;325:1659-60]. N Engl J Med. 1991;324:1829–1838
  59. Fehlings MG, Bracken MB. Summary statement: the Sygen (GM-1 ganglioside) clinical trial in acute spinal cord injury. Spine. 2001;26(24 Suppl):S99–S100
  60. Lee SM, Yune TY, Kim SJ, et al. Minocycline reduces cell death and improves functional recovery after traumatic spinal cord injury in the rat. J Neurotrauma. 2003;20:1017–1027
  61. Knoller N, Auerbach G, Fulga V, et al. Clinical experience using incubated autologous macrophages as a treatment for complete spinal cord injury: phase I study results. J Neurosurg Spine. 2005;3:173–181
  62. Shapiro S, Borgens R, Pascuzzi R, et al. Oscillating field stimulation for complete spinal cord injury in humans: a phase 1 trial. J Neurosurg Spine. 2005;2:3–10
  63. McKerracher L, Higuchi H. Targeting Rho to stimulate repair after spinal cord injury. J Neurotrauma. 2006;23:309–317
  64. Tadie M, Liu S, Robert R, et al. Partial return of motor function in paralyzed legs after surgical bypass of the lesion site by nerve autografts three years after spinal cord injury. J Neurotrauma. 2002;19:909–916
  65. Feron F, Perry C, Cochrane J. Autologous olfactory ensheathing cell transplantation in human spinal cord injury. Brain. 2005;128:2951–2960
  66. Lima C, Pratas-Vital J, Escada P, Hasse-Ferreira A, Capucho C, Peduzzi JD. Olfactory mucosa autografts in human spinal cord injury: a pilot trial. J Spinal Cord Med. 2006;29:191–203; discussion 204-6
  67. Kirshblum S. “A start” (Olfactory mucosa autografts in human spinal cord injury). J Spinal Cord Med. 2006;29:204–206
  68. Huang H, Wang H, Chen L, et al. Influence of patients’ age on functional recovery after transplantation of olfactory ensheathing cells into injured spinal cord injury. Chin Med J. 2003;116:1488–1491
  69. Dobkin BH, Curt A, Guest J. Cellular transplants in China: observational study from the largest human experiment in chronic spinal cord injury. Neurorehabil Neural Repair. 2006;20:5–13
  70. Schwid SR, Petrie MD, McDermott MP, Tierney DS, Mason DH, Goodman AD. Quantitative assessment of sustained-release 4-aminopyridine for symptomatic treatment of multiple sclerosis. Neurology. 1997;48:817–821
  71. Gorman P, Mody V, Jariwala N, et al. Safety and tolerability of HP 184, an oral sodium and potassium channel blocker, in chronic incomplete SCI: a phase II study. Am J Phys Med Rehabil. 2005;84:167–176quiz, 177-9, 198
  72. Anderson DK, Beattie M, Blesch A, et al. Editorial (Recommended guidelines for studies of human subjects with spinal cord injury). Spinal Cord. 2005;43:453–458

 No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.Reprints are not available from the author.

PII: S0003-9993(06)01570-X

doi: 10.1016/j.apmr.2006.12.015

Archives of Physical Medicine and Rehabilitation
Volume 88, Issue 3, Supplement 1 , Pages S76-S83 , March 2007

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