Archives of Physical Medicine and Rehabilitation
Volume 87, Issue 10 , Pages 1305-1309 , October 2006

Prevalence and Natural History of Colonization With Fluoroquinolone-Resistant Gram-Negative Bacilli in Community-Dwelling People With Spinal Cord Dysfunction

Presented in part to the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy, November 2, 2004, Washington, DC, and the American Spinal Injury Association and International Spinal Cord Society, June 27, 2006, Boston, MA.

  • Mary-Claire Roghmann, MD

      Affiliations

    • VA Maryland Health Care System, University of Maryland School of Medicine, Baltimore, MD
    • Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD
    • Corresponding Author InformationCorrespondence to Mary-Claire Roghmann, MD, MS, 100 N Greene St (lower level), Baltimore, MD 21201.
    • ,
  • Mitchell T. Wallin, MD

      Affiliations

    • VA Medical Center, Department of Neurology, Georgetown University School of Medicine, Washington, DC
    • ,
  • Peter H. Gorman, MD

      Affiliations

    • VA Maryland Health Care System, University of Maryland School of Medicine, Baltimore, MD
    • Department of Neurology, University of Maryland School of Medicine, Baltimore, MD
    • ,
  • Judith A. Johnson, PhD

      Affiliations

    • VA Maryland Health Care System, University of Maryland School of Medicine, Baltimore, MD
    • Department of Pathology, University of Maryland School of Medicine, Baltimore, MD

References 

  1. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2003, issued August 2003. Am J Infect Control. 2003;31:481–498
  2. Lautenbach E, Strom BL, Nachamkin I, et al. Longitudinal trends in fluoroquinolone resistance among Enterobacteriaceae isolates from inpatients and outpatients, 1989–2000: differences in the emergence and epidemiology of resistance across organisms. Clin Infect Dis. 2004;38:655–662
  3. Montgomerie JZ. Infections in patients with spinal cord injuries. Clin Infect Dis. 1997;25:1285–1290
  4. Hinkel A, Finke W, Botel U, Gatermann SG, Pannek J. Increasing resistance against antibiotics in bacteria isolated from the lower urinary tract of an outpatient population of spinal cord injury patients. Urol Int. 2004;73:143–148
  5. Penders J, Huylenbroeck AA, Everaert K, Van Laere M, Verschraegen GL. Urinary infections in patients with spinal cord injury. Spinal Cord. 2003;41:549–552
  6. Mylotte JM, Kahler L, Graham R, Young L, Goodnough S. Prospective surveillance for antibiotic-resistant organisms in patients with spinal cord injury admitted to an acute rehabilitation unit. Am J Infect Control. 2000;28:291–297
  7. Mylotte JM, Graham R, Kahler L, Young L, Goodnough S. Epidemiology of nosocomial infection and resistant organisms in patients admitted for the first time to an acute rehabilitation unit. Clin Infect Dis. 2000;30:425–432
  8. Waites KB, Chen Y, DeVivo MJ, Canupp KC, Moser SA. Antimicrobial resistance in gram-negative bacteria isolated from the urinary tract in community-residing persons with spinal cord injury. Arch Phys Med Rehabil. 2000;81:764–769
  9. Dow G, Rao P, Harding G, et al. A prospective, randomized trial of 3 or 14 days of ciprofloxacin treatment for acute urinary tract infection in patients with spinal cord injury. Clin Infect Dis. 2004;39:658–664
  10. Multiple Sclerosis Council for Clinical Practice Guidelines (Urinary dysfunction and multiple sclerosis). New York: National Multiple Sclerosis Society; 1999;
  11. Oken MM, Creech RH, Tormey DC, et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982;5:649–655
  12. Lublin FD, Reingold SC. Defining the clinical course of multiple sclerosis: results of an international survey (National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis). Neurology. 1996;46:907–911
  13. American Spinal Injury Association, International Medical Society of Paraplegia. Standard neurological classification of spinal cord injury. Chicago: ASIA/IMSOP; 2002;
  14. Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing. Wayne: National Committee for Clinical Laboratory Standards; 2006;
  15. Gimber EA, Shields MD, Canawati HN, et al. Bacteriuria with Escherichia coli resistant to ciprofloxacin in patients with spinal-cord injury [letter]. Infect Control Hosp Epidemiol. 1998;19:85–86
  16. Waites KB, Canupp KC, Brookings ES, DeVivo MJ. Effect of oral ciprofloxacin on bacterial flora of perineum, urethra, and lower urinary tract in men with spinal cord injury. J Spinal Cord Med. 1999;22:192–198

 Supported by a VA Merit Review Grant Clinical Science Research and Development, the University of Maryland School of Medicine General Clinical Research Center (grant no. M01-RR-16500), and a Merck Medical School grant.No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.Reprints are not available from the author.

PII: S0003-9993(06)00846-X

doi: 10.1016/j.apmr.2006.07.260

Archives of Physical Medicine and Rehabilitation
Volume 87, Issue 10 , Pages 1305-1309 , October 2006

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