Archives of Physical Medicine and Rehabilitation
Volume 87, Issue 10 , Pages 1352-1356, October 2006

Sleep-Disordered Breathing in Fatigued Postpoliomyelitis Clinic Patients

Presented in part to the American Academy of Physical Medicine and Rehabilitation, October 28, 2005, Philadelphia, PA.

  • Valerie Dahan, MD

      Affiliations

    • Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill, University Health Centre, McGill University, Montreal, QC, Canada
    • Department of Medicine, University of Montreal, Montreal, QC, Canada.
    • ,
  • R. John Kimoff, MD

      Affiliations

    • Respiratory Division and Sleep Laboratory, McGill University Health Centre, McGill University, Montreal, Canada
    • ,
  • Basil J. Petrof, MD

      Affiliations

    • Respiratory Division and Sleep Laboratory, McGill University Health Centre, McGill University, Montreal, Canada
    • ,
  • Andrea Benedetti, PhD

      Affiliations

    • Departments of Medicine and Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada
    • ,
  • Diane Diorio, MD

      Affiliations

    • Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill, University Health Centre, McGill University, Montreal, QC, Canada
    • ,
  • Daria A. Trojan, MD

      Affiliations

    • Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill, University Health Centre, McGill University, Montreal, QC, Canada
    • Corresponding Author InformationCorrespondence to Daria A. Trojan, MD, Montreal Neurological Hospital, McGill University Health Centre, 3801 University St, Montreal, QC H3A 2B4, Canada

Abstract 

Dahan V, Kimoff RJ, Petrof BJ, Benedetti A, Diorio D, Trojan DA. Sleep-disordered breathing in fatigued postpoliomyelitis clinic patients.

Objective

To determine the frequency, predictive factors, and symptoms predictive of sleep-disordered breathing (SDB) in fatigued postpoliomyelitis clinic patients.

Design

Cross-sectional, retrospective chart review.

Setting

University-affiliated hospital postpolio clinic.

Participants

Postpolio clinic charts (N=590) were reviewed. Ninety-eight patients were included, and 492 patients were not included, primarily because of the lack of a polysomnogram.

Interventions

Not applicable.

Main Outcome Measure

The Apnea-Hypopnea Index (AHI) calculated as the total number of sleep-related breathing events/total sleep time.

Results

The frequency of SDB defined by an AHI score of 5 or more was 65% and by an AHI score of 10 or more was 50%. Obstructive hypopnea was the predominant form, occurring in 86%. Age, sex, age at acute polio, time since polio, weakness and respiratory difficulties at acute polio, bulbar involvement at acute polio and at evaluation, body mass index, pulmonary function measures, alcohol use, sedative drug use, smoking, fibromyalgia, kyphoscoliosis, and scoliosis and ear-nose-throat surgery were not predictive of SDB (AHI scores ≥5 and ≥10). Snoring was more common in subjects with SDB (AHI score ≥5 and ≥10). Some pulmonary function measures correlated with oxygen saturation during sleep in SDB (AHI scores ≥5).

Conclusions

SDB was very common in fatigued postpoliomyelitis clinic patients referred for sleep evaluation. Obstructive hypopnea was the most frequent type. In this preliminary study, snoring tended to predict SDB.

Key Words: Poliomyelitis, Rehabilitation, Risk factors, Sleep apnea syndromes

 

 Supported by the Polio Quebec Association and the Montreal Neurological Institute (salary support).No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.

PII: S0003-9993(06)00842-2

doi:10.1016/j.apmr.2006.07.256

Archives of Physical Medicine and Rehabilitation
Volume 87, Issue 10 , Pages 1352-1356, October 2006

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