Archives of Physical Medicine and Rehabilitation
Volume 87, Issue 2 , Pages 241-246 , February 2006

The Effect of 30 Minutes of Passive Stretch of the Rat Soleus Muscle on the Myogenic Differentiation, Myostatin, and Atrogin-1 Gene Expressions

Presented as abstracts to the Federação de Sociedades de Biologia Experimental, August 25–28, 2004, Águas de Lindóia, Brazil, and the American Physiological Society, October 6–9, 2004, Austin, TX.

  • Anna R. Gomes, PT, MS, PhD

      Affiliations

    • Unit of Skeletal Muscle Plasticity, Department of Physical Therapy, Federal University of São Carlos, São Carlos, SP, Brazil
    • ,
  • Antonio G. Soares, TA

      Affiliations

    • Unit of Muscle Morphology, Biomedical Science Institute I, Department of Cell and Developmental Biology, University of São Paulo, São Paulo, SP, Brazil
    • ,
  • Sabrina Peviani, PT, MS

      Affiliations

    • Unit of Skeletal Muscle Plasticity, Department of Physical Therapy, Federal University of São Carlos, São Carlos, SP, Brazil
    • ,
  • Rubia B. Nascimento, PT

      Affiliations

    • Unit of Skeletal Muscle Plasticity, Department of Physical Therapy, Federal University of São Carlos, São Carlos, SP, Brazil
    • ,
  • Anselmo S. Moriscot, PT, MS, PhD

      Affiliations

    • Unit of Muscle Morphology, Biomedical Science Institute I, Department of Cell and Developmental Biology, University of São Paulo, São Paulo, SP, Brazil
    • ,
  • Tania F. Salvini, PT, MS, PhD

      Affiliations

    • Unit of Skeletal Muscle Plasticity, Department of Physical Therapy, Federal University of São Carlos, São Carlos, SP, Brazil
    • Corresponding Author InformationReprint requests to Tania F. Salvini, PT, MS, PhD, Departamento de Fisioterapia, Universidade Federal de São Carlos, CEP 13565-905 São Carlos, SP, Brasil

  • Image Result

    The effect of 30 minutes of passive stretch on the mRNA myoD levels of the rat soleus muscle. (A) Soleus muscle submitted to a single session of stretch, evaluated immediately after (IA), and 8, 24, 4

    The effect of 30 minutes of passive stretch on the mRNA myoD levels of the rat soleus muscle. (A) Soleus muscle submitted to a single session of stretch, evaluated immediately after (IA), and 8, 24, 48, 72, and 168 hours later. (B) Soleus muscle submitted to daily session of stretch and evaluated after 24 hours (received 2 stretches [2st]), 48 hours (received 3 stretches [3st]), and 144 hours (received 7 stretches [7st]). Values are mean ± standard deviation (SD). *P≤.005 (ANOVA), as compared with the control (Cont) group.

  • Image Result
    The effect of 30 minutes of passive stretch on the mRNA myostatin levels of the rat soleus muscle. (A) Soleus muscle submitted to a single session of stretch, evaluated immediately after (IA), and 8,

    The effect of 30 minutes of passive stretch on the mRNA myostatin levels of the rat soleus muscle. (A) Soleus muscle submitted to a single session of stretch, evaluated immediately after (IA), and 8, 24, 48, 72, and 168 hours later. (B) Soleus muscle submitted to daily sessions of stretch and evaluated 24 hours (received 2 stretches), 48 hours (received 3 stretches), and 144 hours (received 7 stretches). Values are mean ± SD.

  • Image Result
    The effect of 30 minutes of passive stretch on the mRNA atrogin-1 levels of the rat soleus muscle. (A) Soleus muscle submitted to a single session of stretch, evaluated immediately after (IA), and 8,

    The effect of 30 minutes of passive stretch on the mRNA atrogin-1 levels of the rat soleus muscle. (A) Soleus muscle submitted to a single session of stretch, evaluated immediately after (IA), and 8, 24, 48, 72, and 168 hours later. (B) Soleus muscle submitted to daily sessions of stretch and evaluated after 24 hours (received 2 stretches), 48 hours (received 3 stretches), and 144 hours (received 7 stretches). Values are mean ± SD. *P≤.005 (ANOVA), as compared with the control group.

 Supported by the Fundação de Amparo à Pesquisa do Estado de São Paulo (grant nos. 01/13523-4, 01/135221-1, 03/10889-3), Coordenção de Aperfeiçoamento de Pessoal de Nivel Superior (grant no. 33001014016P7), and Conselho Nacional de Desenvolvimento Científico e Tecnológico (grant no. 501737/2004-9).No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the authors or upon any organization with which the authors are associated.

PII: S0003-9993(05)01194-9

doi: 10.1016/j.apmr.2005.08.126

Archives of Physical Medicine and Rehabilitation
Volume 87, Issue 2 , Pages 241-246 , February 2006

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