Volume 81, Issue 6 , Pages 764-769, June 2000
Antimicrobial resistance in gram-negative bacteria isolated from the urinary tract in community-residing persons with spinal cord injury☆☆☆★★★♢
Abstract
Waites KB, Chen Y-Y, DeVivo MJ, Canupp KC, Moser SA. Antimicrobial resistance in gram-negative bacteria isolated from the urinary tract in community-residing persons with spinal cord injury. Arch Phys Med Rehabil 2000;81:764-9. Objective: To assess the epidemiology of antimicrobial resistance among community-residing persons with spinal cord injury (SCI). Design: Retrospective analysis of existing data. Setting: Data were obtained from persons with SCI attending clinic for annual examinations. Participants: Two hundred eighty-seven SCI outpatients. Intervention: None. Main Outcome Measure: Occurrence of bacteriuria with gram-negative organisms demonstrating resistance to antimicrobial agents in 2 or more classes. Results: There were 706 gram-negative isolates from 444 urine specimens. Resistance to drugs in 2 or more classes occurred in 33% of bacterial isolates, but did not significantly increase in frequency among those injured for longer periods or more severely. Significantly higher rates of multidrug-resistant bacteria occurred in specimens from males, younger age group (≤45yrs), and persons with indwelling and condom catheters. Conclusions: Antimicrobial resistance in outpatients with SCI is common and is related to widespread use of specific drugs, type of bladder management, and other host factors. © 2000 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation
Keywords: Spinal cord injuries, Urinary tract infections, Bacteriuria, Drug resistance, microbial, Rehabilitation
☆ Supported by grant 1688 from the Paralyzed Veterans of America Spinal Cord Research Foundation and grant H133B980016 from the National Institute on Disability and Rehabilitation Research.
☆☆ No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the authors or upon any organization with which the authors are associated.
★ Reprint requests to Ken B. Waites, MD, Department of Pathology WP 230, 618 South 18th Street, Birmingham, AL 35233.
★★ Supplier
♢ a. Dade MicroScan, Inc., 1584 Enterprise Blvd, West Sacramento, CA 95691.
PII: S0003-9993(00)90108-4
doi:10.1016/S0003-9993(00)90108-4
© 2000 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.
Volume 81, Issue 6 , Pages 764-769, June 2000
